Mullerian inhibiting substance expression in papillary thyroid cancer
نویسندگان
چکیده
منابع مشابه
Regulation of gonadotropin gene expression by Mullerian inhibiting substance.
In addition to its role in causing Müllerian duct regression, Müllerian inhibiting substance (MIS) is implicated in the regulation of steroidogenesis, breast and prostate growth, and ovarian follicle recruitment, all of which are processes controlled or influenced by the hypothalamic-pituitary-gonadal axis. Whereas the direct effect of MIS on gonadal, prostate, and breast cells is under investi...
متن کاملIncidence of thyroid papillary cancer in contralateral lobe
Background & objectives: Prognosis of thyroid papillary cancer is quite well long lasting, so a 10- year survival is observed in more than 90% cases. In this study, rate of incidence of thyroid papillary cancer in contralateral lobe was assessed among patients who had a surgical thyroidectomy re-operation. Materials & Methods: In this retrospective study, we examined 82 patients diagnosed with...
متن کاملExpression of Estrogen and Progesterone Receptors in Papillary Thyroid Carcinoma
Background: Papillary thyroid carcinoma (PTC), occurs mostly in women and sex hormones may play a role in the pathogenesis and clinical course. The objective of this study was to determine the status and prevalence of estrogen and progesterone receptors in PTC with regard to age, gender, tumor size and lymph node involvement. Methods: Immunohistochemical stains were performed on 92 tissue bl...
متن کاملThe nuclear receptor SF-1 mediates sexually dimorphic expression of Mullerian Inhibiting Substance, in vivo.
Mullerian Inhibiting Substance (MIS) functions to promote regression of the Mullerian duct during male development. Maintaining the sexually dimorphic pattern of MIS expression is essential for proper mammalian reproductive tract development. Here, we show that the intricate spatial and temporal pattern of MIS expression is directed by a remarkably small proximal promoter of only 180 base pairs...
متن کاملMullerian inhibiting substance: a gonadal hormone with multiple functions.
Mullerian inhibiting substance (MIS) is the gonadal hormone that causes regression of the Mullerian ducts, the anlagen of the female internal reproductive structures, during male embryogenesis. MIS is a member of the large transforming growth factor-beta (TGF beta) multigene family of glycoproteins that are involved in the regulation of growth and differentiation. The proteins in this gene fami...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Asian Journal of Surgery
سال: 2013
ISSN: 1015-9584
DOI: 10.1016/j.asjsur.2012.11.009